"Knowledge becomes health" - we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 1914. Our around 7,500 employees contribute with their skills and knowledge to the 33 specialist clinics, theoretical clinical institutes, and administrative departments. The close connection of health care with research and teaching, as well as a climate of collegiality, internationality, and cross-professional cooperation characterize the university hospital.
Research Assistant / PhD student
(We are targeting applicants of all genders)
Full time | limited until 36 months | Announcement number: 259-2024
We are looking for a highly motivated PhD student to join a project of the Molecular Radiation Biology group (Head: Prof. Dr. Franz Rödel) at the Department of Radiotherapy and Oncology.
Within a multicenter joint research project “Radiation-induced senescence: Implications for normal tissue toxicity and tumor therapy failure (SeniRad)” granted by the Federal Ministry of Education and Research (BMBF), we aim to investigate radiation-induced senescence in tumor-associated fibroblasts (CAFs) and its significance for the development of a resistance to radiotherapy. The focus is set on the characterization of the underlying regulatory circuits and on non-cell-autonomous effector mechanisms in CAFs and after medium transfer in tumor-organoid models. The relevance of CAF senescence-associated key components as targets of senotherapeutic intervention will be assessed in an orthotopic animal model.
- Planning, organization and independent execution of cell, molecular biological and animal experiments within the scope of the above-mentioned project
- Search of scientific literature, interpretation of results, verification and generation of hypotheses
- Documentation, visualization and publication of research results in scientific journals, presentation of results at seminars and scientific meetings
- Assistance in supervision of students
- Master’s degree in life sciences such as biology, biochemistry or equivalent
- Experiences in basic laboratory techniques (i.e. molecular biology, cell culture)
- A FELASA certificate (or equivalent) is preferred
- Passion for discovery of novel therapeutic approaches
- Ability to work in a team with a collaborative spirit
- A high motivation
- Good communication skills and proficiency in English
- Due to legal regulations, valid proof of measles immunity / measles vaccination is required.
- Collective agreement: In addition to an attractive salary based on a collective agreement (E13 / 65%), with an annual special payment, you benefit from long-term security through company pension schemes
- Mobility: Free public transport in all Hessen (Free State Ticket Hessen)
- Campus: Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk on the riverside of the Main offers relaxation during breaks
- Work-Life-Balance: Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact Ms. Häfner at 069 / 6301 83863), child care during holidays
- Health Promotion: Benefit from our attractive health offers. We offer regular online and face-to-face courses on nutrition, relaxation, sports and exercise.
- Professional development: Internal and external training for your professional development
- Any questions? Many answers can be found in our FAQs for new employees. If you have any further questions, please do not hesitate to contact us.
Disabled applicants are preferred if they have the same personal and professional qualifications.
Use the time until April 15, 2024 to apply. Please submit your application including your CV, short motivation statement (one page max.) and one reference letter. For further information regarding the position and project, please contact Prof. Dr. Franz Rödel (Tel: 069-6301-4838, E-Mail: f.roedel@med.uni-frankfurt.de).
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